cognate trna meaning in Hindi

Examples

1. Aspartyl-tRNA synthetase charges its cognate tRNA with aspartate during protein biosynthesis.
2. This results in the ineffective or complete inability of L-serine to be transferred to its cognate tRNA, resulting in incomplete protein translation and folding.
3. When an m 6 A-modified codon interacts with its cognate tRNA, it acts more like a near-cognate codon interaction instead of the cognate codon interaction.
4. The cytosolic enzyme recognises its cognate tRNA species and binds with a high level of specificity, allowing the accurate interaction between corresponding codons and anticodons on mRNA and tRNA during protein translation.
5. They signal release of the nascent polypeptide from the ribosome because there is no cognate tRNA that has anticodons complementary to these stop signals, and so a release factor binds to the ribosome instead.
6. In translating, or interpreting, the genetic material, they catalyze reactions whereby each amino acid is matched with a nucleotide triplet embedded in its cognate tRNA . In this way, the tRNA synthetases establish the rules of the genetic code and, because of this role, tRNA synthetases are essential for all forms of life.
7. GTP activation and hydrolysis : Codon recognition leads to global conformational changes of the ribosome and tRNA, which are different for cognate or non-cognate tRNAs and affect GTP activation and hydrolysis by EF-Tu . " The conformational proofreading model explains these conformational changes as a means to enhance tRNA recognition . " " inset " : The " symmetric " adapted landscape implies that the ratio of forward and backward rates is inverted between the correct and wrong energy landscapes.
8. An "'aminoacyl tRNA synthetase "'( "'aaRS "') is an enzyme that attaches the appropriate amino acid onto its tRNA . It does so by catalyzing the esterification of a specific cognate amino acid or its precursor to one of all its compatible cognate tRNAs to form an aminoacyl-tRNA . In humans, the 20 different types of aa-tRNA are made by the 20 different aminoacyl-tRNA synthetases, one for each amino acid of the genetic code.